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Aleve vs. Ibuprofen and flaws in Fosbol study Options · View
Larazelle
Posted: Wednesday, June 09, 2010 8:10:59 AM
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So guys after reading the study that DC alerted me to I decided to start with Aleve - I took 2 Aleve tablets last night (440 total) and I still did not sleep through the night without any pain - now does it take about 2 weeks for the inflammatory effect to start to work - well at least the pain should have been alleviated with Aleve don't you think?

So I googled the Fosbol study and I found a few variations from different accounts in various newspapers through the world - first of all this is what the Ethopian review mentioned -

Nevertheless, the study is observational and therefore subject to the possibility of confounding. In addition, important cardiovascular risk factors such as lipid levels, smoking status, blood pressure, and obesity are lacking.

Now I find this unprofessional that they should make such a statement about this drugs without doing any quality control - Also I went through other studies about Ibuprofen and most of them were done on people 80 years old - I am sick of reading studies that are flawed or not conducted well and then they offer it to the general public and make us change the way we live - LOL

Also another newspaper mentioned that regarding Ibuprofen if you take 1200 then you are quite safe -

so I am thinking about this seriously - maybe Aleve does not work well for me and I should start taking Ibuprofen for about 2 weeks - Amber says two weeks minimum and she has been taking this through the life - so anyway I need some feeback from you knowlegeable people



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Amber
Posted: Wednesday, June 09, 2010 9:51:55 AM
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Lara,

Sorry you didn't sleep well again. Unless you're good with sleep dep you need to get this fixed fast.

Err... yes loads of studies sre flawed. You need to see the whole data set and the stats. So much about drugs is politics and $.

I actually said "it takes maybe a week for the full anti-inflammatory effect to kick in" - what docs have told me and what I've found. But yes, it should act immediately as a pain killer. Aleve is the OTC lo-strength version of Naproxyn, right? So this may be an eg of the great variability for response to NSAIDS I mentioned before. Some work for some people, and don't do anything for others.

I have taken many painkillers - but only when needed. Like DCNGA, I have a high pain threshold and therefore make myself more injured as I push on b4 doing anything. I have had a lot of very painful conditions and a few ghastly operations in my life. I can tell you what docs have told me here - v senior docs that I trust (and I trust v few physicians here). And I can tell you my personal experience - but that is not necessarily applicable to you.

If you've got a clean bill of health, I'd put the studies aside and try to find the one that works for you. Maybe try ibuprofen 2 night, or whatever has worked for you b4? Or aspirin with milk, as MissJ suggested?

Good luck hon
Gracey
Posted: Wednesday, June 09, 2010 3:08:09 PM
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DCNGA
Posted: Wednesday, June 09, 2010 3:20:49 PM
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Shepherd is wonderful! Sorry for your son's accident but glad at least that he was someplace where he would get excellent care. I've known several people who've been there and everyone has said how it saved/changed their lives.

As for you migraines, my niece is having surgery with Dr. Guyuron next month for migraines that have incapacitated her for five+ years. I'll post how it turns out for her. She's only 28 and has been robbed of her independence due to these horrid headaches.

DCNGA has left the board and is no longer taking PMs.
She requests that if you wish to e-mail her to use her direct e-mail address which is: laserandiplsupport@gmail.com
Gracey
Posted: Wednesday, June 09, 2010 4:49:24 PM
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Hi DCNGA! Oh, how I can completely relate, and empathize and sympathize with your niece. I'll be sending good vibes and prayers that the surgery is a huge success for her! It's great to hear there's surgery that could help...albeit too late for me. I'm too old, ha. At her age, she should do just fine, and with hope it will give her back a normal life!

As for Shepherd, all that you've heard from others is true. They are miracle workers, no exaggeration. He was in AMC for the first few weeks, and AMC kept him alive and stabilized him over 2 weeks, so technically they get the credit for saving his life in the beginning. But, once conscious, he couldn't talk, walk, eat...nothing. He didn't know who he was, where he was, not even that I was his Mom, and that's how he still was when transferred.

Shephered was life-changing...even for me. Seeing what I saw there has forever changed my perspective about everything in life. What Shepherd did for my son was nothing short of miraculous. Everyone there makes an incredible difference in anyone's lives they touch. One of the EMTs involved in the transfer was about to leave and turned to me and said "I just want you to know that I've seen miracles performed here. Believe in one!".

I have to add that in all the places to which I've ever traveled, I can honestly say that Atlanta has to be the friendliest, kindest of them all. It was my first time there, I was alone, and every day there were total strangers that came up to me with comments of "we'll be praying for you", or simply "I think you need a hug". One woman from GA who was at AMC with family members waiting on word about her husband, who was also critical in SICU, saw I was alone and came up and literally invited me into her family so I wouldn't be alone without moral support. It was shortly before my son's transfer so I didn't take her up on it, but I'll never forget her.

Not kidding, I even walked out of AMC one night to catch a cab to the hotel I was staying at in Marietta. There were gang members standing on the corner of AMC that hospital security had warned me to avoid. I had no choice but to walk past them, and when I was approaching them I just sorta smiled, not knowing what else to do, ha. I swear they parted to let me walk through and actually said "have a good evening". Who would expect it....but it did happen, and on several days they did the same while I passed by them. "Atlanta, where even some of the gang members have compassion", LOL.
DCNGA
Posted: Wednesday, June 09, 2010 6:09:09 PM
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Oooooo AMC area is a little scary. You were brave and kudos to the kids who behaved themselves. Gangs are rampant here, but actually much worse in the outer 'burbs.

As long as you are not driving, people here are really very friendly. I find this to be true in most southern cities, though. There's a lot of physical affection shown down south (and yes, to total strangers) that you just don't see all over. I bet you heard "Bless your heart" many times.

I hope your son is much improved and life is better for him. I pray that I nor anyone in my family ever needs Shepherd but it's nice to have the comfort that they exist if we do.

DCNGA has left the board and is no longer taking PMs.
She requests that if you wish to e-mail her to use her direct e-mail address which is: laserandiplsupport@gmail.com
Larazelle
Posted: Wednesday, June 09, 2010 7:36:25 PM
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Amber wrote:
Lara,


If you've got a clean bill of health, I'd put the studies aside and try to find the one that works for you. Maybe try ibuprofen 2 night, or whatever has worked for you b4? Or aspirin with milk, as MissJ suggested?

Good luck hon



Hi Amber -

Thanks for the concern - I have started taking (with my doctors approval) 600 mg of Ibuprofen twice a day - so that is 1200 which is still a low dose but should work on the inflammation - I took my first dose at 11 a.m. and I already feel better - Yeah - after this heals I am going to "strengthen" my arches by googling for some "foot exercises" -

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MissJ
Posted: Wednesday, June 09, 2010 8:29:06 PM
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You know who is a good foot doctor--Dr. Do. She's really nice. She is on Mass Ave kind of across from the old Marino restaurant.

Can hardly walk. Need hip replacement.
barbiegirl
Posted: Wednesday, June 09, 2010 9:55:57 PM
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Funny how Bugs should mention that she used a turmeric mask today. I ran into a friend of mine who is a prominent ND and he was telling me about this product he loves, has been having great success with his patients and recommended I try for my endo. It is curcumin based, (called Curamin) so a natural anti inflammatory/pain reliever, so it might be worth a shot for you too. I'm going to try it the next time my endo flares badly again and put it to the ultimate test.

"My friends, love is better than anger.
Hope is better than fear.
Optimism is better than despair.
So let us be loving, hopeful and optimistic.
And we’ll change the world."

Larazelle
Posted: Wednesday, June 09, 2010 10:21:23 PM
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MissJ wrote:
You know who is a good foot doctor--Dr. Do. She's really nice. She is on Mass Ave kind of across from the old Marino restaurant.


Thanks Jane - is she Vietnamese - have you seen her personally -



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Gracey
Posted: Thursday, June 10, 2010 2:24:27 AM
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DCNGA wrote:
Oooooo I bet you heard "Bless your heart" many times.

I hope your son is much improved and life is better for him. I pray that I nor anyone in my family ever needs Shepherd but it's nice to have the comfort that they exist if we do.



LOL DCNGA, I did hear that a lot. Thanks, he's doing great! I hope your niece's surgery is a total success for her. I've heard great things about Guyuron, so she'll be in good hands.
Bugjune
Posted: Thursday, June 10, 2010 10:58:02 AM
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I am also sorry you aren't sleeping restfully through the night - boy, can I relate!

And DITTO your comment below!!! It is maddening and even dangerous how these studies are published without any details on the demographics of those studied. I felt that was a key factor in my adverse reaction to the anti-viral, Valtrex. It's typically given to teens and twenty-somethings to treat herpes. So how does that relate to ME, old biddy of 54? >:-(

I hope you get in to see an excellent foot doc, get your orthotics, ask about what you can wear to bed to keep that foot from bothering you. It's debilitating to have a problem area always bonging! BONGING! for attention. Good luck in getting relief.

And know that while you're up googling in the middle of the night, I'm out on my sofa watching the news, sipping an Ensure!

Cheers!


============================
Larazelle wrote:


Now I find this unprofessional that they should make such a statement about this drugs without doing any quality control - Also I went through other studies about Ibuprofen and most of them were done on people 80 years old - I am sick of reading studies that are flawed or not conducted well and then they offer it to the general public and make us change the way we live - LOL



I Bug U
Bugjune
Posted: Thursday, June 10, 2010 11:30:22 AM
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Could be worth a try! I have also been taking one pill of Natural Factors Turmeric & Bromelain per day, that has 300mg turmeric, 250mg curcumin, and 150mg of bromelain. Now, did this concoction prevent the ugly rash on my neck/chest? Doesn't look like it. But did it keep it from getting worse? Dunno! It's maddening trying out all these things: Cetirizine (generic Zyrtec), turmeric paste, lemon water, pure aloe leaf gel, this pill ... I basically have a "credit assignment" problem trying to determine WHICH of these things is worth continuing with, and which - if any - is my silver bullet.

But I will try ANYTHING at least once. It is a fact that thousands die each year from OTC pain relief meds: usually either an overdose or interaction with other med they are taking. So perhaps an herbal supplement would be a safer route to try - but ONLY if you know how it interacts with any other supplement or med you may need to take. Gingko, St. John's Wort, many others seem safe on their own, but are not recommended to take with OTC pain meds due to blood-thinning properties. We have to be a walking encyclopedia to figure all this out.

I am thinking of re-applying the turmeric paste on my mouth area today. I looked like I'd been spawned from a banana yesterday - completely YELLOW mouth area from an hour of having that paste on. But I dare not SCRUB it off!

=================================
barbiegirl wrote:
Funny how Bugs should mention that she used a turmeric mask today. I ran into a friend of mine who is a prominent ND and he was telling me about this product he loves, has been having great success with his patients and recommended I try for my endo. It is curcumin based, (called Curamin) so a natural anti inflammatory/pain reliever, so it might be worth a shot for you too. I'm going to try it the next time my endo flares badly again and put it to the ultimate test.


I Bug U
MissJ
Posted: Thursday, June 10, 2010 4:51:29 PM
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She's Asian but not sure which. Yes, I've seen her.


Larazelle wrote:


Thanks Jane - is she Vietnamese - have you seen her personally -



Can hardly walk. Need hip replacement.
Amber
Posted: Thursday, June 10, 2010 6:45:46 PM
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Location: UK
Larazelle wrote:

Hi Amber -

Thanks for the concern - I have started taking (with my doctors approval) 600 mg of Ibuprofen twice a day - so that is 1200 which is still a low dose but should work on the inflammation - I took my first dose at 11 a.m. and I already feel better - Yeah - after this heals I am going to "strengthen" my arches by googling for some "foot exercises" -


Hi - so how is the ibuprofen going? Should I take no news as good news or is that assumptive?
Larazelle
Posted: Thursday, June 10, 2010 6:53:38 PM
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Amber wrote:


Hi - so how is the ibuprofen going? Should I take no news as good news or is that assumptive?


Hey Amber -

I PMed you -

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Amber
Posted: Thursday, June 10, 2010 6:59:44 PM
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Got it and wrote back.
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